Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14439985 | 0.82 | GAA (0.54) | CYP1A2GAAALDH1A1RECQLTDP1 | |
| SCHEMBL17395725 | 0.80 | GAA (0.59) | CYP1A2GAAALDH1A1RECQLTDP1 | |
| SCHEMBL9684315 | 0.80 | GAA (0.51) | GAAALDH1A1RECQLTDP1 | |
| SCHEMBL9417135 | 0.78 | GAA (0.62) | CYP1A2GAAALDH1A1RECQLTDP1 | |
| SCHEMBL9683399 | 0.78 | GAA (0.50) | GAAALDH1A1RECQLTDP1 | |
| SCHEMBL10439191 | 0.77 | RECQL (0.49) | GAAALDH1A1RECQLTDP1 | |
| SCHEMBL10439345 | 0.77 | RECQL (0.52) | GAAALDH1A1RECQLTDP1 | |
| SCHEMBL9858209 | 0.76 | GAA (0.51) | GAAALDH1A1RECQLTDP1 | |
| SCHEMBL10497028 | 0.75 | GAA (0.57) | CYP1A2GAAALDH1A1RECQLTDP1 | |
| SCHEMBL9674765 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5108994-A | Synergistic with interferon; herpes virus | BEECHAM GROUP P.L.C. (GB) | 1992-04-28 | — | — | US | disclosed |
| EP-0399743-A1 | Phosphonomethylthio-alkoseypureine derivatives, intermediate products for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1990-11-28 | — | — | EP | disclosed |