Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.49 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9673987 | 0.93 | ACAT1 (0.53) | ACAT1SOAT1 | |
| SCHEMBL9674593 | 0.87 | KDM4E (0.55) | KDM4E | |
| SCHEMBL9676301 | 0.84 | ACAT1 (0.50) | ACAT1SOAT1 | |
| SCHEMBL9674747 | 0.84 | KDM4E (0.48) | KDM4EACAT1SOAT1 | |
| SCHEMBL9675878 | 0.82 | KDM4E (0.55) | KDM4EACAT1SOAT1 | |
| SCHEMBL9676130 | 0.81 | KDM4E (0.54) | KDM4EACAT1SOAT1 | |
| SCHEMBL9674220 | 0.80 | ACAT1 (0.54) | KDM4EACAT1SOAT1 | |
| SCHEMBL9674634 | 0.79 | ACAT1 (0.53) | KDM4EACAT1SOAT1 | |
| SCHEMBL9676486 | 0.78 | ACAT1 (0.53) | KDM4EACAT1SOAT1 | |
| SCHEMBL9674584 | 0.78 | ACAT1 (0.53) | ACAT1SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0505481-A1 | 2-SUBSTITUTED 4,5-DIPHENYL-IMIDAZOLES | RHONE-POULENC SANTE (FR) | 1992-09-30 | — | — | EP | disclosed |
| WO-1991009030-A1 | 2-SUBSTITUTED 4,5-DIPHENYL-IMIDAZOLES | RHONE-POULENC SANTE (FR) | 1991-06-27 | — | — | WO | disclosed |