Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | PTGES | O14684 | 1/20 | 0.53 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.51 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9674593 | 0.87 | KDM4E (0.55) | KDM4EPTGES | |
| SCHEMBL9676130 | 0.86 | KDM4E (0.54) | KDM4EPTGESACAT1SOAT1L3MBTL1 | |
| SCHEMBL9675694 | 0.82 | KDM4E (0.50) | KDM4EACAT1SOAT1 | |
| SCHEMBL9215071 | 0.82 | KDM4E (0.68) | KDM4EPTGESALDH1A1LMNAHPGD | |
| SCHEMBL9674220 | 0.80 | ACAT1 (0.54) | KDM4EACAT1SOAT1 | |
| SCHEMBL9673966 | 0.80 | KDM4E (0.53) | KDM4EPTGES | |
| SCHEMBL9674634 | 0.79 | ACAT1 (0.53) | KDM4EACAT1SOAT1 | |
| SCHEMBL9674609 | 0.79 | CYP1A2 (0.54) | KDM4EACAT1SOAT1ALDH1A1 | |
| SCHEMBL8478400 | 0.79 | KDM4E (0.52) | KDM4EPTGES | |
| SCHEMBL9215059 | 0.79 | KDM4E (0.64) | KDM4EPTGESALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0505481-A1 | 2-SUBSTITUTED 4,5-DIPHENYL-IMIDAZOLES | RHONE-POULENC SANTE (FR) | 1992-09-30 | — | — | EP | disclosed |
| WO-1991009030-A1 | 2-SUBSTITUTED 4,5-DIPHENYL-IMIDAZOLES | RHONE-POULENC SANTE (FR) | 1991-06-27 | — | — | WO | disclosed |