Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 9/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | CCR5 | P51681 | 1/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | CCR4 | P51679 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9676649 | 0.93 | OPRM1 (0.61) | OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL10843735 | 0.92 | OPRM1 (0.60) | OPRM1OPRD1OPRK1 | |
| SCHEMBL9677022 | 0.87 | OPRM1 (0.50) | OPRM1OPRD1OPRK1CCR5 | |
| SCHEMBL9675850 | 0.85 | OPRM1 (0.42) | OPRM1OPRD1OPRK1CCR5CARM1 | |
| SCHEMBL19658478 | 0.82 | CCR5 (0.58) | OPRM1OPRD1OPRK1CCR5CACNA1G | |
| SCHEMBL10843469 | 0.79 | OPRM1 (0.60) | OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL10842305 | 0.79 | OPRM1 (0.54) | OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL10842086 | 0.78 | OPRM1 (0.58) | OPRM1OPRD1OPRK1 | |
| SCHEMBL9677638 | 0.78 | OPRM1 (0.53) | OPRM1OPRD1OPRK1 | |
| SCHEMBL9675784 | 0.78 | OPRM1 (0.53) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0160422-B1 | N-ARYL-N-(4-PIPERIDINYL)AMIDES AND PHARMACEUTICAL COMPOSITIONS AND METHODS EMPLOYING SUCH COMPOUNDS | Anaquest, Inc. (US) | 1992-01-08 | — | — | EP | claimed |
| US-4584303-A | ANALGESICS | THE BOC GROUP, INC. (US) | 1986-04-22 | — | — | US | claimed |
| EP-0160422-A1 | N-Aryl-N-(4-Piperidinyl)amides and pharmaceutical compositions and methods employing such compounds | Anaquest, Inc. (US) | 1985-11-06 | — | — | EP | claimed |
| EP-0160422-B1 | N-ARYL-N-(4-PIPERIDINYL)AMIDES AND PHARMACEUTICAL COMPOSITIONS AND METHODS EMPLOYING SUCH COMPOUNDS | Anaquest, Inc. (US) | 1992-01-08 | — | — | EP | disclosed |