Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9673861 | 0.97 | CHRM2 (0.47) | CHRM2CHRM1 | |
| SCHEMBL9675425 | 0.97 | CHRM2 (0.47) | CHRM2CHRM1 | |
| SCHEMBL9676036 | 0.95 | CHRM2 (0.48) | CHRM2CHRM1 | |
| SCHEMBL9674009 | 0.94 | CHRM2 (0.48) | CHRM2 | |
| SCHEMBL9678379 | 0.93 | — | — | |
| SCHEMBL9674158 | 0.93 | CHRM2 (0.47) | CHRM2CHRM1 | |
| SCHEMBL9674043 | 0.93 | — | — | |
| SCHEMBL9673959 | 0.91 | CHRM2 (0.54) | CHRM2CHRM4CHRM1 | |
| Hydrochloric Acid SCHEMBL9675612 | 0.91 | LMNA (0.55) | CHRM2CHRM4CHRM1 | |
| Hydrochloric Acid SCHEMBL9673831 | 0.90 | LMNA (0.54) | CHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306698-B1 | CONDENSED DIAZEPINONES, PROCESSES FOR THEIR PREPARATION, AND MEDICAMENTS CONTAINING THESE COMPOUNDS | Dr. Karl Thomae GmbH (DE) | 1992-03-25 | — | — | EP | disclosed |
| US-4931436-A | BRADYCARDIAL AGENTS | DR. KARL THOMAE GMBH (DE) | 1990-06-05 | — | — | US | disclosed |