SCHEMBL967660

SCHEMBL967660

COC(=O)C(S)[Zn]C(S)C(=O)OC

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.42
CA14 Q9ULX7 2/20 0.36
CA12 O43570 1/20 0.33
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.32
ZDHHC7 Q9NXF8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL964380 0.74 ALDH1A1 (0.43) KMT2AALDH1A1HSD17B10
SCHEMBL963290 0.74 TSHR (0.42) CA14CA12CA1CA2TSHR
SCHEMBL10329462 0.73 SMN1; SMN2 (0.48) SMN1; SMN2CA14CA12KMT2AALDH1A1
SCHEMBL5755090 0.73
SCHEMBL2035273 0.73 SMN1; SMN2 (0.48) SMN1; SMN2CA14CA12KMT2AALDH1A1
SCHEMBL7640960 0.73 SMN1; SMN2 (0.48) SMN1; SMN2CA14CA12KMT2AALDH1A1
SCHEMBL2598147 0.71
SCHEMBL932508 0.71
SCHEMBL964588 0.70 HCAR2 (0.38) SMN1; SMN2ALDH1A1TSHRHSD17B10
SCHEMBL6698356 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2280057-B2 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE IDEMITSU KOSAN CO (JP) 2016-11-23 EP disclosed
US-9321981-B2 Lubricating oil composition for internal combustion engine IDEMITSU KOSAN CO., LTD. (JP) 2016-04-26 US disclosed
EP-2280057-B1 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE IDEMITSU KOSAN CO (JP) 2013-09-11 EP disclosed
EP-2280057-A1 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE Idemitsu Kosan Co., Ltd. (JP) 2011-02-02 EP disclosed
US-20110021393-A1 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE IDEMITSU KOSAN CO., LTD. (JP) 2011-01-27 US disclosed