Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 2/20 | 0.40 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9677180 | 1.00 | CRBN (0.42) | CRBNMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6267844 | 0.86 | ALDH1A1 (0.41) | MAPTNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL10537759 | 0.86 | ALDH1A1 (0.41) | MAPTNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL9678330 | 0.83 | CRBN (0.46) | CRBNMAPTSMN1; SMN2ALDH1A1GRM5 | |
| SCHEMBL10534352 | 0.81 | ALDH1A1 (0.40) | MAPTNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL10534347 | 0.81 | ALDH1A1 (0.40) | MAPTNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL9677209 | 0.80 | DRD2 (0.51) | MAPTNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL6262429 | 0.80 | DRD2 (0.51) | MAPTNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL9677194 | 0.80 | DRD2 (0.51) | MAPTNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL6260664 | 0.77 | DRD2 (0.56) | MAPTNPC1RAB9ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268229-B1 | IMIDAZOLIDINONE COMPOUNDS, PROCESSES FOR PREPARATION THEREOF, COMPOSITIONS COMPRISING SUCH COMPOUNDS, AND THE USE OF SUCH COMPOUNDS FOR THE MANUFACTURE OF MEDICAMENTS HAVING THERAPEUTIC VALUE | TANABE SEIYAKU CO., LTD. (JP) | 1992-07-08 | — | — | EP | disclosed |