Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 8/20 | 0.39 |
| ▸ | GABRD | O14764 | 8/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 8/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 8/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 8/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 8/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 8/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 8/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 8/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 8/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 8/20 | 0.39 |
| ▸ | GABRE | P78334 | 8/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 8/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 8/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 8/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 8/20 | 0.39 |
| ▸ | KDM1A | O60341 | 6/20 | 0.38 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9677316 | 1.00 | GABRP (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9678423 | 0.82 | GABRP (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9636515 | 0.74 | GABRP (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8950509 | 0.74 | GABRP (0.63) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8950400 | 0.74 | GABRP (0.63) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9636600 | 0.74 | GABRP (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2564135 | 0.70 | MAPT (0.47) | KDM1ARCOR1MAPTSMN1; SMN2TDP1 | |
| SCHEMBL10980305 | 0.69 | ALDH1A1 (0.53) | KDM1ARCOR1MAPTALDH1A1 | |
| SCHEMBL8752146 | 0.69 | ALDH1A1 (0.53) | KDM1ARCOR1MAPTALDH1A1 | |
| SCHEMBL6860853 | 0.68 | MAPT (0.35) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0294228-B1 | NOVEL HETEROCYCLIC PESTICIDAL COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-08-26 | — | — | EP | claimed |
| EP-0294228-A2 | Novel heterocyclic pesticidal compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1988-12-07 | — | — | EP | disclosed |