Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9311427 | 0.94 | AGTR1 (0.39) | BRD4AGTR1AGTR2 | |
| SCHEMBL9310413 | 0.93 | MKNK2 (0.33) | BRD4 | |
| SCHEMBL9678265 | 0.92 | EDNRA (0.32) | BRD4P2RX7 | |
| SCHEMBL9311293 | 0.92 | AGTR2 (0.35) | BRD4AGTR1AGTR2P2RX7 | |
| SCHEMBL9678077 | 0.89 | BRD4 (0.32) | BRD4P2RX7 | |
| SCHEMBL9309506 | 0.88 | EDNRA (0.35) | AGTR1AGTR2 | |
| SCHEMBL9310584 | 0.87 | AGTR1 (0.36) | BRD4AGTR1AGTR2 | |
| SCHEMBL9311216 | 0.87 | AGTR1 (0.36) | AGTR1AGTR2 | |
| SCHEMBL9309104 | 0.87 | MKNK2 (0.34) | BRD4AGTR1AGTR2P2RX7 | |
| SCHEMBL9310231 | 0.86 | AGTR2 (0.42) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514216-A1 | Antihypotensive benzofuran derivatives with N-linked 1H-imidazolyl-methyl-5-carboxamide substituents | GLAXO GROUP LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |