Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.53 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 10/20 | 0.53 |
| ▸ | CNR2 | P34972 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678910 | 1.00 | KDM4E (0.53) | KDM4ETP53CYP3A4MAPTALOX15 | |
| SCHEMBL9498573 | 0.87 | CNR1 (0.66) | KDM4ETP53CYP3A4MAPTALOX15 | |
| SCHEMBL10716137 | 0.87 | CNR1 (0.59) | KDM4ETP53CYP3A4MAPTALOX15 | |
| SCHEMBL9446334 | 0.87 | CNR1 (0.66) | KDM4ETP53CYP3A4MAPTALOX15 | |
| SCHEMBL9446331 | 0.87 | CNR1 (0.66) | KDM4ETP53CYP3A4MAPTALOX15 | |
| SCHEMBL9498564 | 0.87 | CNR1 (0.66) | KDM4ETP53CYP3A4MAPTALOX15 | |
| SCHEMBL9498071 | 0.87 | CNR1 (0.66) | KDM4ETP53CYP3A4MAPTALOX15 | |
| SCHEMBL9858218 | 0.85 | CNR1 (0.63) | CNR1CNR2 | |
| SCHEMBL9857303 | 0.85 | CNR1 (0.63) | CNR1CNR2 | |
| SCHEMBL9857301 | 0.85 | CNR1 (0.63) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | claimed |
| US-5153226-A | Administering as anticholesterol agents, for atherosclerosis | WARNER-LAMBERT COMPANY (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |