Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.51 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.51 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9679723 | 0.82 | SOAT2 (0.57) | KMT2ASOAT2SOAT1MEP1BLMNA | |
| SCHEMBL9679386 | 0.81 | KMT2A (0.55) | KMT2AMEN1LMNA | |
| SCHEMBL9679376 | 0.81 | KMT2A (0.55) | KMT2AMEN1LMNA | |
| SCHEMBL9851068 | 0.80 | — | — | |
| SCHEMBL9848403 | 0.78 | — | — | |
| SCHEMBL9848470 | 0.78 | — | — | |
| SCHEMBL9679244 | 0.76 | KMT2A (0.52) | KMT2AMEN1LMNA | |
| SCHEMBL9000626 | 0.75 | SOAT2 (0.50) | KMT2AMEN1SOAT2SOAT1LMNA | |
| SCHEMBL6719402 | 0.75 | TP53 (0.56) | KMT2AMEN1LMNA | |
| SCHEMBL9679740 | 0.75 | KMT2A (0.58) | KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | claimed |
| US-5153226-A | Administering as anticholesterol agents, for atherosclerosis | WARNER-LAMBERT COMPANY (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |