Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9679376 | 1.00 | KMT2A (0.55) | KMT2ALMNATP53MEN1THRB | |
| SCHEMBL6719402 | 0.93 | TP53 (0.56) | KMT2ALMNATP53MEN1THRB | |
| SCHEMBL6722718 | 0.83 | MEN1 (0.64) | KMT2ALMNATP53MEN1THRB | |
| SCHEMBL9678908 | 0.81 | KMT2A (0.51) | KMT2ALMNAMEN1 | |
| SCHEMBL8337684 | 0.79 | CTSS (0.54) | KMT2ATP53MEN1THRB | |
| SCHEMBL5799250 | 0.79 | KMT2A (0.58) | KMT2ALMNAMEN1 | |
| SCHEMBL9679740 | 0.79 | KMT2A (0.58) | KMT2ALMNAMEN1SMN1; SMN2 | |
| SCHEMBL6716780 | 0.78 | CRHBP (0.61) | KMT2ALMNATP53MEN1SMN1; SMN2 | |
| SCHEMBL6715723 | 0.77 | MEN1 (0.55) | KMT2AMEN1THRB | |
| SCHEMBL8845511 | 0.77 | KMT2A (0.68) | KMT2ALMNAMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | claimed |
| US-5153226-A | Administering as anticholesterol agents, for atherosclerosis | WARNER-LAMBERT COMPANY (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |