SCHEMBL9679154

SCHEMBL9679154

O=C(Oc1cccc2c1-c1ccccc1-2)c1cccc(C(=O)Oc2cccc3c2-c2ccccc2-3)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TOP1 P11387 1/20 0.56
SLC2A1 P11166 1/20 0.48
SLC2A4 P14672 1/20 0.48
KMT2A Q03164 8/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
MAPT P10636 2/20 0.47
SLC6A3 Q01959 1/20 0.46
SERPINE1 P05121 1/20 0.46
ESR1 P03372 3/20 0.45
ESR2 Q92731 3/20 0.45
MEN1 O00255 2/20 0.45
GAA P10253 2/20 0.45
HSD17B10 Q99714 2/20 0.45
JAK2 O60674 1/20 0.45
USP2 O75604 1/20 0.45
ALOX15 P16050 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
PTGES O14684 1/20 0.45
ALOX5 P09917 1/20 0.43
POLB P06746 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9337991 0.89 TOP1 (0.59) TOP1KMT2ASMN1; SMN2MAPTSLC6A3
SCHEMBL17744831 0.81 TOP1 (0.51) TOP1SLC2A1SLC2A4KMT2ASMN1; SMN2
SCHEMBL27961252 0.78 TOP1 (0.46) TOP1KMT2ASMN1; SMN2MAPTSLC6A3
SCHEMBL27512237 0.77 KDM4E (0.52) KMT2ASMN1; SMN2MAPTESR1MEN1
SCHEMBL689023 0.77 ESR1 (0.62) TOP1SLC2A1SLC2A4KMT2ASMN1; SMN2
SCHEMBL10786907 0.77 KMT2A (0.56) TOP1SLC2A1SLC2A4KMT2ASMN1; SMN2
SCHEMBL29905085 0.77 SLC2A1 (0.69) SLC2A1SLC2A4KMT2ASMN1; SMN2MAPT
SCHEMBL2402122 0.77 TOP1 (0.41) TOP1KMT2ASMN1; SMN2MAPTESR1
SCHEMBL17744832 0.76 TOP1 (0.50) TOP1KMT2ASMN1; SMN2MAPTSLC6A3
SCHEMBL6367155 0.76 TOP1 (0.69) TOP1KMT2ASMN1; SMN2MAPTSLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0472366-A2 Crystalline wholly aromatic polyester, process for its production, resin composition containing it, and articles from the resin composition TEIJIN LIMITED (JP) 1992-02-26 EP disclosed