Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 1/20 | 0.69 |
| ▸ | PTGES | O14684 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11524597 | 0.97 | TOP1 (0.66) | TOP1PTGESKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL11525810 | 0.91 | EGFR (0.60) | TOP1PTGESKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL11529372 | 0.89 | EGFR (0.57) | TOP1PTGESKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL6367150 | 0.85 | ESR1 (0.56) | TOP1PTGESKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL27584326 | 0.85 | S100A4 (0.57) | TOP1PTGESKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL6366348 | 0.83 | KMT2A (0.58) | TOP1PTGESKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL16473011 | 0.82 | TOP1 (0.64) | TOP1PTGESKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL27584375 | 0.82 | KMT2A (0.55) | TOP1PTGESKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9680641 | 0.82 | TOP1 (0.64) | TOP1PTGESKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL12827331 | 0.82 | TOP1 (1.00) | TOP1PTGESKMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050009924-A1 | Synthesis and pharmaceuticals of novel bis-substituted anthraquinone derivatives | HUANG HSU-SHAN (TW) | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009924-A1 | Synthesis and pharmaceuticals of novel bis-substituted anthraquinone derivatives | NFE2L2, NR2F2, TFAM | TOP1 3100/4885PTGES 2969/4885KMT2A 1696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.