SCHEMBL17744832

SCHEMBL17744832

Nc1ccccc1-c1c(N)cccc1OC(=O)c1cccc(C(=O)O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TOP1 P11387 1/20 0.50
SMN1; SMN2 Q16637 4/20 0.43
TSHR P16473 1/20 0.43
KMT2A Q03164 5/20 0.42
MAPT P10636 3/20 0.42
TTR P02766 2/20 0.41
SLC6A3 Q01959 1/20 0.41
PTGES O14684 1/20 0.41
MEN1 O00255 2/20 0.40
USP2 O75604 2/20 0.40
ESR1 P03372 2/20 0.40
ESR2 Q92731 2/20 0.40
JAK2 O60674 1/20 0.40
GAA P10253 1/20 0.40
ALOX15 P16050 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
HSD17B10 Q99714 1/20 0.40
LMNA P02545 2/20 0.40
PTGER1 P34995 1/20 0.40
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17744831 0.94 TOP1 (0.51) TOP1SMN1; SMN2TSHRKMT2AMAPT
SCHEMBL17744863 0.89 TOP1 (0.52) TOP1SMN1; SMN2TSHRKMT2AMAPT
SCHEMBL17744861 0.86 TOP1 (0.54) TOP1SMN1; SMN2TSHRKMT2AMAPT
SCHEMBL17744782 0.82 KDM4C (0.43) TOP1SMN1; SMN2TSHRKMT2AMAPT
SCHEMBL10786907 0.81 KMT2A (0.56) TOP1SMN1; SMN2TSHRKMT2AMAPT
SCHEMBL17744774 0.81 HSD17B10 (0.50) TOP1TSHRKMT2AMAPTSLC6A3
SCHEMBL17744773 0.80 HSD17B10 (0.44) TOP1SMN1; SMN2TSHRKMT2AMAPT
SCHEMBL13292712 0.79 SMN1; SMN2 (0.62) TOP1SMN1; SMN2TSHRKMT2AMAPT
SCHEMBL17783723 0.77 KMO (0.43) TOP1SMN1; SMN2KMT2AMAPTMEN1
SCHEMBL30335393 0.76 KMT2A (0.56) TOP1SMN1; SMN2TSHRKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10400076-B2 Epoxy resin composition, prepreg, and carbon fiber-reinforced composite material TORAY INDUSTRIES, INC. (JP) 2019-09-03 US disclosed
EP-3020763-B1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES (JP) 2018-08-29 EP disclosed
US-20160152785-A1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 2016-06-02 US disclosed
EP-3020763-A1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL Toray Industries, Inc. (JP) 2016-05-18 EP disclosed