SCHEMBL967959

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13985808	0.89	PARP1 (0.52)	USP2ALDH1A1MAPTMAPK1PARP1
	SCHEMBL970353	0.89	PARP1 (0.52)	USP2ALDH1A1MAPTPARP1KDM4E
	SCHEMBL967791	0.89	NPC1 (0.58)	USP2ALDH1A1MAPTPARP1KDM4E
	SCHEMBL970324	0.86	ALDH1A1 (0.64)	ALDH1A1MAPTPARP1KDM4EHPGD
	SCHEMBL967938	0.86	HDAC1 (0.54)	USP2ALDH1A1PARP1KDM4EHPGD
	SCHEMBL968649	0.86	PARP1 (0.50)	USP2ALDH1A1MAPTMAPK1PARP1
	SCHEMBL969089	0.85	PARP1 (0.65)	ALDH1A1MAPTPARP1KDM4EHPGD
	SCHEMBL968434	0.84	ALDH1A1 (0.64)	ALDH1A1MAPTPARP1KDM4EHPGD
	SCHEMBL968632	0.84	PARP1 (0.48)	USP2ALDH1A1MAPTMAPK1PARP1
	SCHEMBL967118	0.83	ALDH1A1 (0.63)	ALDH1A1MAPTPARP1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.