SCHEMBL970353

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL970441	0.92	PARP1 (0.52)	PARP1ALDH1A1HPGDKDM4EUSP2
	SCHEMBL967959	0.89	USP2 (0.54)	PARP1ALDH1A1HPGDKDM4EBAZ2B
	SCHEMBL967791	0.89	NPC1 (0.58)	PARP1ALDH1A1HPGDKDM4EBAZ2B
	SCHEMBL13985808	0.89	PARP1 (0.52)	PARP1ALDH1A1HPGDKDM4EBAZ2B
	SCHEMBL970324	0.86	ALDH1A1 (0.64)	PARP1ALDH1A1HPGDKDM4EHDAC1
	SCHEMBL968649	0.86	PARP1 (0.50)	PARP1ALDH1A1HPGDKDM4EUSP2
	SCHEMBL967938	0.86	HDAC1 (0.54)	PARP1ALDH1A1HPGDKDM4EBAZ2B
	SCHEMBL969089	0.85	PARP1 (0.65)	PARP1ALDH1A1HPGDKDM4EHDAC1
	SCHEMBL968434	0.84	ALDH1A1 (0.64)	PARP1ALDH1A1HPGDKDM4EHDAC1
	SCHEMBL971431	0.84	PARP1 (0.49)	PARP1ALDH1A1HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.