Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21295617 | 0.75 | ESR1 (0.42) | — | |
| SCHEMBL28869362 | 0.69 | SLC6A2 (0.32) | — | |
| SCHEMBL21295754 | 0.68 | KDM4E (0.37) | — | |
| SCHEMBL26184965 | 0.66 | MAPT (0.38) | — | |
| SCHEMBL28583818 | 0.66 | HDAC3 (0.45) | — | |
| SCHEMBL28869311 | 0.65 | XDH (0.33) | — | |
| SCHEMBL891238 | 0.63 | GPR55 (0.41) | — | |
| SCHEMBL21295978 | 0.63 | KDM4E (0.50) | — | |
| SCHEMBL4802079 | 0.62 | — | — | |
| SCHEMBL4805256 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0479892-A1 | FUSED-RING ARYL SUBSTITUTED IMIDAZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-04-15 | — | — | EP | disclosed |