Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP8 | P40818 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CHKA | P35790 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752307 | 0.98 | ALDH1A1 (0.40) | USP8ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL1328314 | 0.72 | NPC1 (0.41) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL11548897 | 0.70 | ALDH1A1 (0.58) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL9831669 | 0.69 | EGFR (0.49) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL31013493 | 0.68 | ALDH1A1 (0.62) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL2174173 | 0.67 | ALDH1A1 (0.67) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL9752257 | 0.67 | USP8 (0.43) | USP8ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL20836338 | 0.66 | ALDH1A1 (0.41) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL327765 | 0.66 | ADRB1 (0.64) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL25472520 | 0.66 | MAOB (0.44) | USP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991001312-A1 | NOVEL PHOTOACTIVE COMPOUNDS | MTM RESEARCH CHEMICALS LIMITED (GB) | 1991-02-07 | — | — | WO | claimed |
| EP-0484390-A1 | NOVEL PHOTOACTIVE COMPOUNDS | MTM RESEARCH CHEMICALS LIMITED (GB) | 1992-05-13 | — | — | EP | disclosed |
| WO-1991001312-A1 | NOVEL PHOTOACTIVE COMPOUNDS | MTM RESEARCH CHEMICALS LIMITED (GB) | 1991-02-07 | — | — | WO | disclosed |