Furan

Furan

SCHEMBL9679795

C=CC(=O)Cl.c1ccoc1

nearest known ligand 0.42

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Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
LMNA P02545 1/20 0.32
AKT1 P31749 1/20 0.31
ALDH1A1 P00352 2/20 0.30
TSHR P16473 1/20 0.30
FGFR4 P22455 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Furan SCHEMBL28248449 0.97 MAPK1 (0.40) MAPK1TDP1LMNAAKT1
Acrylic Acid SCHEMBL29006811 0.81 LMNA (0.56) MAPK1TDP1LMNAAKT1ALDH1A1
Acrylic Acid SCHEMBL3048137 0.81 LMNA (0.56) MAPK1TDP1LMNAAKT1ALDH1A1
Furan SCHEMBL27593818 0.80
Benzene SCHEMBL27986867 0.80 LMNA (0.50) MAPK1TDP1LMNAAKT1ALDH1A1
Furan SCHEMBL27750543 0.80 MAPK1 (0.57) MAPK1TDP1
Furan SCHEMBL27966877 0.79 ALDH1A1 (0.58) MAPK1TDP1LMNAAKT1ALDH1A1
Acrylic Acid SCHEMBL27308194 0.79 LMNA (0.53) MAPK1TDP1LMNAAKT1ALDH1A1
Furan SCHEMBL10622719 0.78 MAPT (0.47) TDP1LMNAALDH1A1
Furan SCHEMBL9016053 0.77 MAPK1 (0.53) MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111793048-B Polyfunctional furan acrylate derivative and application thereof in preparation of furan ring-containing polyester 合肥工业大学 2023-09-26 CN disclosed
CN-114573502-A Pleuromutilin aromatic heterocyclic acrylate compounds and synthesis method and application thereof 西安康远晟生物医药科技有限公司 2022-06-03 CN disclosed
CN-111793048-A Multifunctional furan acrylate derivative and application thereof in preparation of furan ring-containing polyester 合肥工业大学 2020-10-20 CN disclosed
CN-105732505-B Acryloyl amination arylpyrazole type compound and its solvent heat one-pot synthesis and application 中南民族大学 2018-10-12 CN disclosed
CN-105732505-A Acrylamidoaryl pyrazole compounds, and one-pot synthesis method and application thereof 中南民族大学 2016-07-06 CN disclosed
EP-0150507-B1 CEPHALOSPORIN DERIVATIVES, PROCESSES FOR PRODUCING THE SAME AND COMPOSITIONS CONTAINING THEM MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1992-08-05 EP disclosed
US-5064953-A INTERMEDIATES CEPHALOSPORIN DERIVATIVES MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1991-11-12 US disclosed
EP-0365844-A2 Easily curable photoresist SIEMENS AKTIENGESELLSCHAFT (DE) 1990-05-02 EP disclosed
US-4888332-A ANTIBIOTICS MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1989-12-19 US disclosed
US-4732843-A Irradiation cross-linkable thermostable polymer system, for microelectronic applications SIEMENS AKTIENGESELLSCHAFT (DE) 1988-03-22 US disclosed
EP-0150507-A2 Cephalosporin derivatives, processes for producing the same and compositions containing them MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1985-08-07 EP disclosed