Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680354 | 0.85 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| SCHEMBL9680744 | 0.81 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| SCHEMBL10458497 | 0.79 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| SCHEMBL9680452 | 0.79 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| SCHEMBL9679519 | 0.78 | SMN1; SMN2 (0.61) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| SCHEMBL4206450 | 0.78 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| SCHEMBL10941442 | 0.77 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| SCHEMBL10940747 | 0.77 | SMN1; SMN2 (0.72) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| SCHEMBL3667774 | 0.77 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| SCHEMBL10456875 | 0.77 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |