Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | PHGDH | O43175 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681072 | 0.87 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| SCHEMBL22355416 | 0.87 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| SCHEMBL9681331 | 0.86 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| SCHEMBL10458798 | 0.82 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| SCHEMBL10458525 | 0.82 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| SCHEMBL23805897 | 0.81 | SRD5A2 (0.52) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| SCHEMBL10885245 | 0.81 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| SCHEMBL10942634 | 0.81 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| SCHEMBL10943047 | 0.81 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| SCHEMBL10944580 | 0.81 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642296-B2 | 2-hydroxy-1-(4-hydroxymethyl-phenyl)-2-methyl-propan-1-one, have higher reactivity at the benzylic hydroxy group and do not have a tendency to yellowing; photocurable composition for pigmented or non-pigmented varnish surface coatings | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-01-05 | — | — | US | disclosed |
| US-20070240609-A1 | Photoinitiators | IGM GROUP B.V. (NL) | 2007-10-18 | — | — | US | disclosed |
| EP-1763499-B1 | NEW PHOTOINITIATORS | CIBA SC HOLDING AG (CH) | 2007-09-26 | — | — | EP | disclosed |