SCHEMBL9680110

SCHEMBL9680110

[NH]c1nc(Cl)nc(F)c1Cl

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9181490 0.80 ALDH1A1 (0.47) ALDH1A1ALOX15TSHR
SCHEMBL9336416 0.79
SCHEMBL9471045 0.72 ALDH1A1 (0.39) ALDH1A1ALOX15TSHR
SCHEMBL8114120 0.69
SCHEMBL9680116 0.68 ALDH1A1 (0.35) ALDH1A1ALOX15TSHR
SCHEMBL11248114 0.68 ALDH1A1 (0.35) ALDH1A1ALOX15TSHR
SCHEMBL1598822 0.67 ALDH1A1 (0.47) ALDH1A1ALOX15TSHR
SCHEMBL11118869 0.65 ALDH1A1 (0.32) ALDH1A1ALOX15TSHR
SCHEMBL11115462 0.65 ALDH1A1 (0.32) ALDH1A1ALOX15TSHR
SCHEMBL9787166 0.64 MEN1 (0.32) ALDH1A1ALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5128455-A WATER-SOLUBLE FIBER-REACTIVE DYES, CONTAINING AN AMINO-SUBSTITUTED 5-TRIAZINE RING WITH A FIBER-REACTIVE GROUP OF THE VINYLSULFONE SERIES HOECHST AKTIENGESELLSCHAFT (DE) 1992-07-07 US disclosed
US-4948879-A Monoazo compounds containing a fiber-reactive group and an oxazolopyridone or oxazinopyridone coupling component HOECHST AKTIENGESELLSCHAFT (DE) 1990-08-14 US disclosed
EP-0374911-A1 Water-soluble, fibre-reactive dyes, methods for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-06-27 EP disclosed