Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NT5E | P21589 | 3/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 2/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.37 |
| ▸ | CASP6 | P55212 | 2/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680181 | 0.77 | NT5E (0.44) | ALDH1A1HSD17B10KDM4EHPGDLCK | |
| SCHEMBL9756727 | 0.77 | HSD17B10 (0.65) | ALDH1A1HSD17B10KDM4EHPGDLCK | |
| SCHEMBL5193607 | 0.76 | ALDH1A1 (0.59) | ALDH1A1HSD17B10KDM4EHPGDLCK | |
| SCHEMBL9756732 | 0.75 | HSD17B10 (0.62) | ALDH1A1HSD17B10KDM4EHPGDLCK | |
| Sulfosalicylic SCHEMBL6717073 | 0.73 | ALDH1A1 (0.96) | ALDH1A1HSD17B10KDM4EHPGDMEN1 | |
| Sulfosalicylic SCHEMBL34766 | 0.73 | ALDH1A1 (0.96) | ALDH1A1HSD17B10KDM4EHPGDMEN1 | |
| Sulfosalicylic SCHEMBL29364125 | 0.73 | ALDH1A1 (0.96) | ALDH1A1HSD17B10KDM4EHPGDMEN1 | |
| Sulfosalicylic SCHEMBL29157636 | 0.72 | ALDH1A1 (0.86) | ALDH1A1HSD17B10KDM4EHPGDMEN1 | |
| Sulfosalicylic SCHEMBL25356542 | 0.72 | ALDH1A1 (0.93) | ALDH1A1HSD17B10KDM4EHPGDMEN1 | |
| Sulfosalicylic SCHEMBL16908545 | 0.72 | ALDH1A1 (0.93) | ALDH1A1HSD17B10KDM4EHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128455-A | WATER-SOLUBLE FIBER-REACTIVE DYES, CONTAINING AN AMINO-SUBSTITUTED 5-TRIAZINE RING WITH A FIBER-REACTIVE GROUP OF THE VINYLSULFONE SERIES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-07-07 | — | — | US | disclosed |
| US-4912244-A | Vinylsulfonylalkylamino-alkylamines as intermediates for the preparation of fiber-reactive dyes | CIBA-GEIGY CORPORATION (US) | 1990-03-27 | — | — | US | disclosed |
| US-4782140-A | Triazinyl reactive dyes containing additional fiber reactive groups bound through the sulfonylalkylaminoalkylamino bridge | CIBA-GIEGY CORPORATION (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0144766-B1 | REACTIVE DYES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1988-10-05 | — | — | EP | disclosed |
| US-4754023-A | Reactive dyestuffs comprising a triazine moiety and a vinylsulfonyl moiety both being linked by a substituted alkylene bridge member | CIBA-GEIGY CORPORATION (US) | 1988-06-28 | — | — | US | disclosed |
| EP-0159292-B1 | REACTIVE DYES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1988-01-07 | — | — | EP | disclosed |
| EP-0159292-A2 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1985-10-23 | — | — | EP | disclosed |
| EP-0144766-A2 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1985-06-19 | — | — | EP | disclosed |