Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 2/20 | 0.52 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681145 | 0.85 | SOAT2 (0.56) | SOAT2SOAT1KMT2AMEN1LMNA | |
| SCHEMBL9678665 | 0.85 | KMT2A (0.47) | SOAT2SOAT1KMT2AMEN1LMNA | |
| SCHEMBL9680204 | 0.83 | SOAT2 (0.51) | SOAT2SOAT1KMT2AMEN1LMNA | |
| SCHEMBL6899771 | 0.83 | SOAT1 (0.62) | SOAT2SOAT1KMT2AMEN1LMNA | |
| SCHEMBL9679390 | 0.82 | ALDH1A1 (0.58) | SOAT2SOAT1KMT2AMEN1LMNA | |
| SCHEMBL9679857 | 0.82 | SOAT2 (0.57) | SOAT2SOAT1KMT2AMEN1LMNA | |
| SCHEMBL9679656 | 0.81 | SOAT2 (0.60) | SOAT2SOAT1KMT2AMEN1LMNA | |
| SCHEMBL9463360 | 0.80 | SOAT2 (0.55) | SOAT2SOAT1KMT2AMEN1LMNA | |
| SCHEMBL11143056 | 0.79 | ALDH1A1 (0.58) | SOAT2SOAT1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL9844078 | 0.78 | SOAT1 (0.56) | SOAT2SOAT1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153226-A | Administering as anticholesterol agents, for atherosclerosis | WARNER-LAMBERT COMPANY (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |