SCHEMBL9680223

SCHEMBL9680223

CCC(C(=O)C(CC)c1ccc(-c2ccc(Br)cc2)cc1)c1ccc(-c2ccc(Br)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.44
KMT2A Q03164 1/20 0.41
RAB9A P51151 1/20 0.40
ALOX5 P09917 1/20 0.40
HAO1 Q9UJM8 1/20 0.40
MMP1 P03956 1/20 0.38
MMP2 P08253 1/20 0.38
MMP3 P08254 1/20 0.38
MMP7 P09237 1/20 0.38
MMP9 P14780 1/20 0.38
MMP13 P45452 1/20 0.38
LMNA P02545 1/20 0.38
HSD17B10 Q99714 1/20 0.38
DHODH Q02127 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9680703 0.94 CYP1A2 (0.48) CYP1A2KMT2ARAB9AALOX5LMNA
SCHEMBL9680287 0.85 KMT2A (0.43) CYP1A2KMT2AALOX5HAO1
SCHEMBL6766 0.82 KMT2A (0.53) CYP1A2KMT2ALMNAHSD17B10
SCHEMBL25377657 0.82 KMT2A (0.53) CYP1A2KMT2ALMNAHSD17B10
SCHEMBL2720268 0.81 ALOX5 (0.47) CYP1A2KMT2ARAB9AALOX5MMP9
SCHEMBL10443280 0.79 KMT2A (0.43) CYP1A2KMT2ARAB9AALOX5LMNA
SCHEMBL11785517 0.79 CA1 (0.44) CYP1A2KMT2ARAB9AALOX5LMNA
SCHEMBL9679404 0.78 KMT2A (0.46) CYP1A2KMT2AALOX5
SCHEMBL6293 0.78 MAPT (0.46) CYP1A2KMT2ARAB9ALMNA
SCHEMBL18129416 0.78 CYP1A2 (0.44) CYP1A2KMT2AALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5136013-A Polyesters BAYER AKTIENGESELLSCHAFT (DE) 1992-08-04 US disclosed
US-5068300-A BIFUNCTIONAL STILBENE COMPOUNDS CONTAINING AT LEAST ONE Z-CONFIGURATED STILBENE GROUP, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR THE PREPARATION OF POLYMERS BAYER AKTIENGESELLSCHAFT (DE) 1991-11-26 US disclosed