Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 8/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 8/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25377657 | 1.00 | KMT2A (0.53) | KMT2AAKR1C3AKR1C2PTGS1AKR1C1 | |
| SCHEMBL1574429 | 0.89 | AKR1C3 (0.58) | AKR1C3AKR1C2PTGS1AKR1C1HTR1A | |
| SCHEMBL9680703 | 0.88 | CYP1A2 (0.48) | KMT2ACYP1A2GAALMNAHSD17B10 | |
| SCHEMBL6431696 | 0.85 | KMT2A (0.50) | KMT2APTGS1CYP1A2ALDH1A1GAA | |
| SCHEMBL6431027 | 0.85 | KMT2A (0.50) | KMT2APTGS1CYP1A2ALDH1A1GAA | |
| SCHEMBL10443280 | 0.85 | KMT2A (0.43) | KMT2ACYP1A2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL9680223 | 0.82 | CYP1A2 (0.44) | KMT2ACYP1A2LMNAHSD17B10 | |
| SCHEMBL2720268 | 0.82 | ALOX5 (0.47) | KMT2ACYP1A2 | |
| SCHEMBL27835623 | 0.82 | KMT2A (0.41) | KMT2ACYP1A2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL27721904 | 0.82 | KMT2A (0.41) | KMT2ACYP1A2ALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11225500-B2 | Synthesis of 1:1:1 co-crystal of 1-cyano-2-(4-cyclopropyl-benzyl)-4-(β-D-glucopyranos-1-yl)-benzene, L-proline and water | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2022-01-18 | — | — | US | claimed |
| US-20210139520-A1 | SYNTHESIS OF 1:1:1 CO-CRYSTAL OF 1-CYANO-2-(4-CYCLOPROPYL-BENZYL)-4-(ß-D-GLUCOPYRANOS-1-YL)-BENZENE, L-PROLINE AND WATER | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2021-05-13 | — | — | US | claimed |
| EP-3668846-A1 | SYNTHESIS OF THE 1 :1 :1 CO-CRYSTAL OF 1 -CYANO-2-(4-CYCLOPROPYL-BENZYL)-4-(BETA-D-GLUCOPYRANOS-1 -YL)-BENZENE, L-PROLINE AND WATER | Boehringer Ingelheim Vetmedica GmbH (DE) | 2020-06-24 | — | — | EP | claimed |
| US-20250145561-A1 | 4-SUBSTITUTED-PHENYL ACETAMIDES AND ARYLUREAS AS AGONISTS FOR THE ORPHAN RECEPTOR GPR88 | RESEARCH TRIANGLE INSTITUTE (US) | 2025-05-08 | — | — | US | disclosed |
| CN-119823032-A | Anticancer compounds | 悉尼大学 | 2025-04-15 | — | — | CN | disclosed |
| CN-111741944-B | Anticancer compounds | 悉尼大学 | 2025-01-03 | — | — | CN | disclosed |
| EP-4469431-A1 | 4-SUBSTITUTED-PHENYL ACETAMIDES AND ARYLUREAS AS AGONISTS FOR THE ORPHAN RECEPTOR GPR88 | Research Triangle Institute (US) | 2024-12-04 | — | — | EP | disclosed |
| US-20240199621-A1 | MAP4K4 INHIBITORS | IMPERIAL COLLEGE INNOVATIONS LTD (GB) | 2024-06-20 | — | — | US | disclosed |
| US-20240182421-A1 | SYNTHESIS OF ENDOCHIN-LIKE QUINOLONES | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2024-06-06 | — | — | US | disclosed |
| US-20240182419-A1 | ANTI-CANCER COMPOUNDS | THE UNIVERSITY OF SYDNEY (AU) | 2024-06-06 | — | — | US | disclosed |
| US-11939296-B2 | Anti-cancer compounds | THE UNIVERSITY OF SYDNEY (AU) | 2024-03-26 | — | — | US | disclosed |
| US-6340691-B1 | TREATMENT OF ARTHRITIS, TUMOR METASTASIS, TISSUE ULCERATION, ABNORMAL WOUND HEALING, PERIODONTAL DISEASE, BONE DISEASE, DIABETES (INSULIN RESISTANCE) AND HIV INFECTION | AMERICAN CYANAMID COMPANY | 2002-01-22 | — | — | US | disclosed |
| EP-1147080-A1 | ALKYNYL CONTAINING HYDROXAMIC ACID COMPOUNDS AS TACE INHIBITORS | American Cyanamid Company (US) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000044713-A1 | ALKYNYL CONTAINING HYDROXAMIC ACID COMPOUNDS AS TACE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 2000-08-03 | — | — | WO | disclosed |
| WO-2000035881-A1 | QUATERNIZED WATER SOLUBLE VINYLPYRIDINE CARBOXYLATE POLYMERS | ISP INVESTMENTS, INC. (US) | 2000-06-22 | — | — | WO | disclosed |
| EP-0838448-A1 | Process for the separation of a mixture of enantiomers | DSM N.V. (NL) | 1998-04-29 | — | — | EP | disclosed |
| US-5723666-A | USEFUL AS REGULATORS OF CELL PROLIFERATION AND DIFFERENTIATION | ALLERGAN (US) | 1998-03-03 | — | — | US | disclosed |
| EP-0294220-B1 | Photopolymerizable composition | HITACHI CHEMICAL CO LTD (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5034429-A | An unsaturated monomer, a photoinitiator and a benzene derivative for providing a cured film | HITACHI CHEMICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0294220-A2 | Photopolymerizable composition | Hitachi Chemical Co., Ltd. (JP) | 1988-12-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11225500-B2 | Synthesis of 1:1:1 co-crystal of 1-cyano-2-(4-cyclopropyl-benzyl)-4-(β-D-glucopyranos-1-yl)-benzene, L-proline and water | COL1A1, DCXR, PLOD1 | KMT2A 4210/4885AKR1C3 637/4885AKR1C2 336/4885 |
| US-20240182421-A1 | SYNTHESIS OF ENDOCHIN-LIKE QUINOLONES | ENGASE, ESYT2, VPS4B | KMT2A 1560/4885AKR1C3 3917/4885AKR1C2 3245/4885 |
| US-20210139520-A1 | SYNTHESIS OF 1:1:1 CO-CRYSTAL OF 1-CYANO-2-(4-CYCLOPROPYL-BENZYL)-4-(ß-D-GLUCOPYRANOS-1-YL)-BENZENE, L-PROLINE AND WATER | COL1A1, DCXR, PLOD1 | KMT2A 4201/4885AKR1C3 627/4885AKR1C2 331/4885 |
| US-11939296-B2 | Anti-cancer compounds | MKI67, TP53, CDK5 | KMT2A 1315/4885AKR1C3 3799/4885AKR1C2 3051/4885 |
| US-20240182419-A1 | ANTI-CANCER COMPOUNDS | MKI67, TP53, CDK5 | KMT2A 1315/4885AKR1C3 3799/4885AKR1C2 3051/4885 |
| US-20250145561-A1 | 4-SUBSTITUTED-PHENYL ACETAMIDES AND ARYLUREAS AS AGONISTS FOR THE ORPHAN RECEPTOR GPR88 | GPR88, GPR84, GPR139 | KMT2A 823/4885AKR1C3 2169/4885AKR1C2 1416/4885 |
| US-20240199621-A1 | MAP4K4 INHIBITORS | MAP4K4, MAP4K2, MAP4K5 | KMT2A 1775/4885AKR1C3 906/4885AKR1C2 833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.