SCHEMBL9680244

SCHEMBL9680244

Sc1ccc(/C=C/c2ccc(Cl)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.68
AHR P35869 1/20 0.58
CYP1A2 P05177 2/20 0.48
ALOX5 P09917 1/20 0.47
PTGS1 P23219 1/20 0.47
PTGS2 P35354 1/20 0.47
NFE2L2 Q16236 1/20 0.47
HSD17B10 Q99714 2/20 0.46
FBP1 P09467 1/20 0.45
KDM4E B2RXH2 2/20 0.44
ALDH1A1 P00352 1/20 0.44
MAPK1 P28482 1/20 0.44
MAPT P10636 1/20 0.44
HDAC2 Q92769 1/20 0.44
LMNA P02545 1/20 0.42
CYP2A6 P11509 1/20 0.42
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
DAO P14920 1/20 0.41
MAOB P27338 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9680249 1.00 IDO1 (0.68) IDO1AHRCYP1A2ALOX5PTGS1
SCHEMBL2632276 0.90 IDO1 (0.62) IDO1AHRCYP1A2ALOX5PTGS1
SCHEMBL443909 0.86 IDO1 (0.42) IDO1AHRCYP1A2ALOX5PTGS1
SCHEMBL9680702 0.86 IDO1 (0.42) IDO1AHRCYP1A2ALOX5PTGS1
SCHEMBL443908 0.86 IDO1 (0.42) IDO1AHRCYP1A2ALOX5PTGS1
SCHEMBL9679426 0.86 AHR (0.74) AHRCYP1A2ALOX5PTGS1PTGS2
SCHEMBL699666 0.86 AHR (0.74) AHRCYP1A2ALOX5PTGS1PTGS2
SCHEMBL260347 0.86 AHR (0.74) AHRCYP1A2ALOX5PTGS1PTGS2
SCHEMBL20582895 0.86 AHR (0.74) AHRCYP1A2ALOX5PTGS1PTGS2
SCHEMBL1795502 0.86 AHR (0.74) AHRCYP1A2ALOX5PTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5136013-A Polyesters BAYER AKTIENGESELLSCHAFT (DE) 1992-08-04 US disclosed