Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | CCR6 | P51684 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | PTGIR | P43119 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7105658 | 0.87 | OPRK1 (0.45) | ALDH1A1TDP1L3MBTL1KMT2AMAPK1 | |
| SCHEMBL7105650 | 0.85 | TDP1 (0.44) | ALDH1A1TDP1L3MBTL1KMT2AMAPK1 | |
| SCHEMBL9135166 | 0.85 | ALDH1A1 (0.52) | ALDH1A1TDP1L3MBTL1KMT2AMAPK1 | |
| SCHEMBL9118903 | 0.85 | ALDH1A1 (0.55) | ALDH1A1TDP1L3MBTL1KMT2AMAPK1 | |
| SCHEMBL17092997 | 0.85 | ATM (0.53) | ALDH1A1TDP1L3MBTL1KMT2AATM | |
| SCHEMBL24729148 | 0.84 | ALDH1A1 (0.44) | ALDH1A1TDP1L3MBTL1KMT2AMAPK1 | |
| SCHEMBL12606466 | 0.84 | PTGIR (0.49) | ALDH1A1TDP1L3MBTL1KMT2AMAPK1 | |
| SCHEMBL7288194 | 0.83 | ALDH1A1 (0.53) | ALDH1A1TDP1L3MBTL1KMT2AMAPK1 | |
| SCHEMBL24729192 | 0.83 | ALDH1A1 (0.56) | ALDH1A1TDP1L3MBTL1KMT2AMAPK1 | |
| SCHEMBL16964891 | 0.82 | TDP1 (0.59) | ALDH1A1TDP1L3MBTL1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153226-A | Administering as anticholesterol agents, for atherosclerosis | WARNER-LAMBERT COMPANY (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |