Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 3/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | RARB | P10826 | 5/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.44 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.44 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.44 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RARA | P10276 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680228 | 0.94 | PLAAT3 (0.49) | HDAC2HDAC1HDAC8RARBHDAC3 | |
| SCHEMBL9679405 | 0.94 | HDAC1 (0.49) | HDAC2HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL1377057 | 0.88 | PLAAT3 (0.53) | HDAC2HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL9680739 | 0.86 | MMP12 (0.55) | HDAC2HDAC8FFAR1 | |
| SCHEMBL9680364 | 0.84 | HDAC1 (0.45) | HDAC2HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL11756466 | 0.81 | HDAC2 (0.60) | HDAC2HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL1114650 | 0.81 | MAPT (0.66) | HDAC2HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL4685861 | 0.81 | MEN1 (0.52) | HDAC2HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL4484073 | 0.80 | FFAR1 (0.53) | FFAR1 | |
| SCHEMBL25176127 | 0.79 | MAPT (0.69) | HDAC2HDAC1HDAC8HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5136013-A | Polyesters | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-04 | — | — | US | disclosed |
| US-5068300-A | BIFUNCTIONAL STILBENE COMPOUNDS CONTAINING AT LEAST ONE Z-CONFIGURATED STILBENE GROUP, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR THE PREPARATION OF POLYMERS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-11-26 | — | — | US | disclosed |