Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10889539 | 0.84 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| SCHEMBL10889886 | 0.81 | ALDH1A1 (0.81) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| SCHEMBL10886640 | 0.81 | ALDH1A1 (0.81) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| SCHEMBL10884364 | 0.81 | ALDH1A1 (0.81) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| SCHEMBL27554 | 0.80 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| SCHEMBL14246539 | 0.80 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| Hydrochloric Acid SCHEMBL727298 | 0.79 | ALDH1A1 (0.97) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| SCHEMBL10885949 | 0.78 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| SCHEMBL21824684 | 0.78 | ALDH1A1 (0.94) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| SCHEMBL10886078 | 0.78 | SMN1; SMN2 (0.74) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| US-4582862-A | QUICK-SETTING PRINTING INKS BASED ON ACRYLATED RESINS | CIBA-GEIGY CORPORATION (US) | 1986-04-15 | — | — | US | disclosed |