Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | PTPRC | P08575 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | APAF1 | O14727 | 3/20 | 0.45 |
| ▸ | CASP3 | P42574 | 2/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.45 |
| ▸ | S100A4 | P26447 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9679962 | 0.99 | HPGD (0.62) | HPGDALDH1A1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL10942591 | 0.97 | HPGD (0.61) | HPGDALDH1A1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL9680983 | 0.95 | ALDH1A1 (0.58) | HPGDALDH1A1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL9680469 | 0.95 | ALDH1A1 (0.58) | HPGDALDH1A1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL10945947 | 0.93 | ALDH1A1 (0.57) | HPGDALDH1A1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL9680419 | 0.87 | NPC1 (0.63) | HPGDALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9681708 | 0.85 | SMN1; SMN2 (0.49) | HPGDALDH1A1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL10941099 | 0.85 | SMN1; SMN2 (0.49) | HPGDALDH1A1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL9680508 | 0.85 | NPC1 (0.60) | HPGDALDH1A1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL10946337 | 0.84 | NPC1 (0.59) | HPGDALDH1A1TSHRSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| EP-0138754-B1 | PHOTOCURABLE COMPOSITIONS | CIBA-GEIGY AG (CH) | 1988-05-25 | — | — | EP | disclosed |
| EP-0138754-A2 | Photocurable compositions | CIBA-GEIGY AG (CH) | 1985-04-24 | — | — | EP | disclosed |
| US-4496447-A | PHOTOPOLYMERIZATION OF UNSATURATED COMPOUNDS AND FOR CURING PRINTING INKS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1985-01-29 | — | — | US | disclosed |
| US-4374984-A | Aromatic-aliphatic ketones useful as photoinitiators | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-02-22 | — | — | US | disclosed |