Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | PTPRC | P08575 | 3/20 | 0.45 |
| ▸ | CDC25A | P30304 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | S100A4 | P26447 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10946337 | 0.99 | NPC1 (0.59) | NPC1RAB9AALDH1A1L3MBTL1GAA | |
| SCHEMBL9680419 | 0.99 | NPC1 (0.63) | NPC1RAB9AALDH1A1L3MBTL1GAA | |
| SCHEMBL10943943 | 0.96 | ALDH1A1 (0.54) | NPC1RAB9AALDH1A1L3MBTL1GAA | |
| SCHEMBL10944726 | 0.94 | ALDH1A1 (0.52) | NPC1RAB9AALDH1A1L3MBTL1GAA | |
| SCHEMBL10948642 | 0.93 | ALDH1A1 (0.54) | NPC1RAB9AALDH1A1L3MBTL1GAA | |
| SCHEMBL9679962 | 0.86 | HPGD (0.62) | NPC1RAB9AALDH1A1L3MBTL1GAA | |
| SCHEMBL10947824 | 0.86 | L3MBTL1 (0.45) | NPC1RAB9AALDH1A1L3MBTL1GAA | |
| SCHEMBL9680435 | 0.86 | SRD5A1 (0.48) | NPC1RAB9AALDH1A1L3MBTL1GAA | |
| SCHEMBL9680476 | 0.85 | HPGD (0.64) | NPC1RAB9AALDH1A1L3MBTL1GAA | |
| SCHEMBL10942591 | 0.85 | HPGD (0.61) | NPC1RAB9AALDH1A1L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| EP-0138754-B1 | PHOTOCURABLE COMPOSITIONS | CIBA-GEIGY AG (CH) | 1988-05-25 | — | — | EP | disclosed |
| US-4496447-A | PHOTOPOLYMERIZATION OF UNSATURATED COMPOUNDS AND FOR CURING PRINTING INKS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1985-01-29 | — | — | US | disclosed |
| US-4374984-A | Aromatic-aliphatic ketones useful as photoinitiators | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-02-22 | — | — | US | disclosed |