Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9965307 | 0.73 | CA1 (0.43) | MAPTALDH1A1 | |
| SCHEMBL8348766 | 0.72 | ALDH1A1 (0.44) | MAPTALDH1A1 | |
| SCHEMBL11122429 | 0.72 | ALDH1A1 (0.44) | MAPTALDH1A1 | |
| SCHEMBL1073890 | 0.72 | ALDH1A1 (0.44) | MAPTALDH1A1 | |
| SCHEMBL7014418 | 0.72 | ALDH1A1 (0.44) | MAPTALDH1A1 | |
| SCHEMBL10153255 | 0.71 | — | — | |
| SCHEMBL7638534 | 0.69 | MAPT (0.44) | MAPTALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL3844858 | 0.68 | — | — | |
| SCHEMBL8348774 | 0.66 | — | — | |
| SCHEMBL8348928 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1022319-C | 1, 2, 3, 4-tetrahydronaphthalene derivatives, process for their preparation and their use as medicaments | MERRELL DOW PHARMA (US) | 1993-10-06 | — | — | CN | disclosed |
| US-5106861-A | Method of using certain tetralin derivatives to produce analgesic relief | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-04-21 | — | — | US | disclosed |
| US-5041673-A | Aminopeptidase inhibitors, immunomodulators, analgesics | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-08-20 | — | — | US | disclosed |
| EP-0381902-A1 | Tetralin derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-08-16 | — | — | EP | disclosed |
| CN-1044460-A | Novel 1,2,3,4-tetralin derivative | MERRELL DOW PHARMA (US) | 1990-08-08 | — | — | CN | disclosed |
| EP-0378456-A1 | Tetralin derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-07-18 | — | — | EP | disclosed |