Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681888 | 0.87 | ALDH1A1 (0.57) | ALDH1A1MAPTGAAALOX5RAB9A | |
| SCHEMBL4990373 | 0.85 | KMT2A (0.49) | ALDH1A1MAPTTDP1MEN1POLB | |
| SCHEMBL27696384 | 0.82 | ALDH1A1 (0.58) | ALDH1A1MAPTGAAALOX5KDM4E | |
| SCHEMBL9448725 | 0.82 | ALOX5 (0.65) | ALDH1A1MAPTGAATDP1ALOX5 | |
| SCHEMBL31124079 | 0.81 | KMT2A (0.47) | ALDH1A1MAPTTDP1MEN1POLB | |
| SCHEMBL4598444 | 0.81 | KMT2A (0.47) | ALDH1A1MAPTTDP1MEN1POLB | |
| SCHEMBL31124167 | 0.81 | KMT2A (0.47) | ALDH1A1MAPTTDP1MEN1POLB | |
| SCHEMBL23417690 | 0.80 | ALDH1A1 (0.62) | ALDH1A1MAPTTDP1CES2CES1 | |
| SCHEMBL9680648 | 0.80 | KMT2A (0.59) | ALDH1A1MAPTGAATDP1KDM4E | |
| SCHEMBL4204276 | 0.79 | KMT2A (0.51) | ALDH1A1MAPTGAATDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153335-A | Reacting halophthalic anhydride and alkali metal salt with acid or acid derivative catalyst | OCCIDENTAL CHEMICAL CORPORATION (US) | 1992-10-06 | — | — | US | claimed |
| EP-0460687-A2 | Process for the preparation of oxydiphthalic anhydride and acyloxyphthalic anhydrides | OCCIDENTAL CHEMICAL CORPORATION (US) | 1991-12-11 | — | — | EP | claimed |
| US-5153335-A | Reacting halophthalic anhydride and alkali metal salt with acid or acid derivative catalyst | OCCIDENTAL CHEMICAL CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0460687-A2 | Process for the preparation of oxydiphthalic anhydride and acyloxyphthalic anhydrides | OCCIDENTAL CHEMICAL CORPORATION (US) | 1991-12-11 | — | — | EP | disclosed |