Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
| ▸ | HK1 | P19367 | 1/20 | 0.30 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31430885 | 0.77 | ALDH1A1 (0.32) | POLB | |
| SCHEMBL11625865 | 0.74 | — | — | |
| SCHEMBL8873959 | 0.71 | ALOX15 (0.39) | POLBALOX5ALOX15TSHR | |
| SCHEMBL10333187 | 0.65 | POLB (0.35) | POLBALOX5NLRP3 | |
| SCHEMBL31587885 | 0.64 | POLB (0.34) | POLBALOX5NLRP3 | |
| SCHEMBL11183540 | 0.63 | ALOX15 (0.39) | POLBALOX5ALOX15TSHR | |
| SCHEMBL25090572 | 0.63 | POLB (0.42) | POLBALOX5ALOX15TSHR | |
| SCHEMBL8959105 | 0.63 | POLB (0.40) | POLBALOX5ALOX15TSHR | |
| SCHEMBL18510216 | 0.63 | POLB (0.40) | POLBALOX5ALOX15TSHR | |
| SCHEMBL27640654 | 0.61 | POLB (0.32) | POLBALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63049099-A | — | — | None | — | — | JP | disclosed |
| US-5093250-A | Process for producing optically active bicyclo[3.3.0]octanedione carboxylic acid esters | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | disclosed |
| JP-S6349099-A | PRODUCTION OF OPTICALLY ACTIVE 3-CHLORO-4-HYDROXY-2-CYCLOPENTENONE | FUJI YAKUHIN KOGYO KK | 1988-03-01 | — | — | JP | disclosed |