SCHEMBL9680756

SCHEMBL9680756

Nc1nc(F)nc(Cl)c1Cl

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KHK P50053 1/20 0.32
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9336420 0.79 MEN1 (0.31)
SCHEMBL9682575 0.75 IDO1 (0.38)
SCHEMBL9178065 0.72
SCHEMBL5491792 0.72 TDP1 (0.38) TDP1
SCHEMBL1182747 0.72 ALDH1A1 (0.39) TDP1
SCHEMBL9647756 0.69 TDP1 (0.34) KHKTDP1
SCHEMBL6401815 0.69 PDE4A (0.33)
SCHEMBL14165804 0.68 HTT (0.35) TDP1
SCHEMBL29484711 0.68 HTT (0.35) TDP1
SCHEMBL9680751 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5128455-A WATER-SOLUBLE FIBER-REACTIVE DYES, CONTAINING AN AMINO-SUBSTITUTED 5-TRIAZINE RING WITH A FIBER-REACTIVE GROUP OF THE VINYLSULFONE SERIES HOECHST AKTIENGESELLSCHAFT (DE) 1992-07-07 US disclosed
US-4948879-A Monoazo compounds containing a fiber-reactive group and an oxazolopyridone or oxazinopyridone coupling component HOECHST AKTIENGESELLSCHAFT (DE) 1990-08-14 US disclosed
EP-0316779-A2 Pyridone azo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1989-05-24 EP disclosed