Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.59 |
| ▸ | CHKA | P35790 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HBB | P68871 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.41 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9135564 | 0.92 | CHRM5 (0.70) | CHRM5CHKATSHRMAPTSMN1; SMN2 | |
| Diethylaniline SCHEMBL6907129 | 0.88 | TSHR (0.59) | CHKATSHRMAPTSMN1; SMN2TAAR1 | |
| SCHEMBL6199563 | 0.86 | CHRM5 (0.80) | CHRM5CHKATSHRMAPTSMN1; SMN2 | |
| Diethylaniline SCHEMBL9376796 | 0.84 | TSHR (0.55) | TSHRMAPTSMN1; SMN2TAAR1CNR2 | |
| SCHEMBL49134 | 0.84 | CHRM5 (0.52) | CHRM5CHKATSHRMAPTSMN1; SMN2 | |
| Diethylaniline SCHEMBL27431980 | 0.82 | TSHR (0.53) | TSHRMAPTSMN1; SMN2TAAR1CNR2 | |
| Hydrochloric Acid SCHEMBL7861604 | 0.82 | ALDH1A1 (0.50) | CHRM5CHKATSHRMAPTSMN1; SMN2 | |
| Benzene SCHEMBL28113160 | 0.82 | CHRM5 (0.89) | CHRM5CHKATSHRMAPTSMN1; SMN2 | |
| Diethylaniline SCHEMBL10706433 | 0.80 | TSHR (0.64) | TSHRMAPTTAAR1CNR2KMT2A | |
| Diethylaniline SCHEMBL17594 | 0.79 | TSHR (0.70) | TSHRMAPTTAAR1CNR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5154755-A | Uracil derivatives and herbicides containing the same as active ingredient | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0489480-A1 | Uracil derivatives and herbicides containing the same as active ingredient | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-06-10 | — | — | EP | disclosed |
| US-5084084-A | Uracil and thiouracil derivatives | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-01-28 | — | — | US | disclosed |