SCHEMBL9680962

SCHEMBL9680962

O=C(Cl)CC(Cl)(Cl)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29007494 0.79
SCHEMBL16941870 0.77 TSHR (0.35) TSHRALDH1A1TP53
SCHEMBL7690034 0.77 ACLY (0.42) TSHRALDH1A1TP53
SCHEMBL61462 0.75
SCHEMBL28661533 0.75 TSHR (0.38) TSHRALDH1A1TP53
SCHEMBL16385276 0.74 TSHR (0.33) TSHRALDH1A1TP53
SCHEMBL24410838 0.72 TSHR (0.38) TSHRALDH1A1TP53
SCHEMBL1726464 0.72 THRB (0.33) TSHR
SCHEMBL7170616 0.72 TSHR (0.32) TSHR
SCHEMBL1649559 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3123753-A None JP disclosed
US-5093522-A Intermediates for finishing textiles BAYER AKTIENGESELLSCHAFT (DE) 1992-03-03 US disclosed
JP-H03123753-A CARBOXYLIC ACID HALIDE HAVING TRIFLUOROMETHYL GROUP AND PREPARATION OF THE SAME BAYER AG 1991-05-27 JP disclosed