Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | OGG1 | O15527 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9679717 | 0.94 | KMT2A (0.41) | KMT2AMEN1RAB9ANPC1CES2 | |
| SCHEMBL9679720 | 0.88 | CYP1A2 (0.46) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL897098 | 0.84 | KMT2A (0.43) | KMT2AMEN1RAB9ANPC1CES2 | |
| SCHEMBL3052505 | 0.84 | KMT2A (0.41) | KMT2AMEN1RAB9ANPC1CES2 | |
| SCHEMBL1141785 | 0.82 | KMT2A (0.63) | KMT2AMEN1RAB9ANPC1CES2 | |
| SCHEMBL6673950 | 0.80 | KMT2A (0.41) | KMT2AMEN1RAB9ANPC1CES2 | |
| SCHEMBL6628 | 0.79 | KMT2A (0.49) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL31058225 | 0.79 | RORC (0.42) | KMT2AMEN1RAB9ANPC1CES2 | |
| SCHEMBL3986556 | 0.79 | MEN1 (0.42) | KMT2AMEN1RAB9ANPC1CES2 | |
| SCHEMBL7753912 | 0.78 | ESR1 (0.56) | KMT2AMEN1RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107344918-B | Diphenyl ethylene-containing oxime ester compounds and preparation method and application thereof | 同济大学 | 2020-06-16 | — | — | CN | disclosed |
| CN-107344918-A | A kind of oxime ester compound containing talan and its preparation method and application | 同济大学 | 2017-11-14 | — | — | CN | disclosed |
| US-5136013-A | Polyesters | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-04 | — | — | US | disclosed |
| US-5068300-A | BIFUNCTIONAL STILBENE COMPOUNDS CONTAINING AT LEAST ONE Z-CONFIGURATED STILBENE GROUP, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR THE PREPARATION OF POLYMERS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-11-26 | — | — | US | disclosed |