Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | OGG1 | O15527 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3497043 | 0.88 | MAPT (0.52) | KMT2AMAPTAPPAKR1C3AKR1C2 | |
| SCHEMBL9681020 | 0.84 | KMT2A (0.42) | KMT2AMAPTNPC1RAB9AMEN1 | |
| SCHEMBL6673950 | 0.83 | KMT2A (0.41) | KMT2AMAPTNPC1RAB9AMEN1 | |
| SCHEMBL3052505 | 0.82 | KMT2A (0.41) | KMT2AMAPTNPC1RAB9AMEN1 | |
| SCHEMBL27998567 | 0.82 | HDAC1 (0.45) | KMT2AMAPTNPC1RAB9AMEN1 | |
| SCHEMBL7361290 | 0.82 | MEN1 (0.41) | KMT2ANPC1RAB9AMEN1CES2 | |
| SCHEMBL18982634 | 0.82 | MEN1 (0.41) | KMT2ANPC1RAB9AMEN1CES2 | |
| SCHEMBL4664901 | 0.81 | SRD5A2 (0.54) | KMT2AMAPTNPC1RAB9AMEN1 | |
| SCHEMBL31058225 | 0.81 | RORC (0.42) | KMT2AMAPTNPC1RAB9AMEN1 | |
| SCHEMBL1141785 | 0.80 | KMT2A (0.63) | KMT2AMAPTNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104876853-B | The synthetic method of fexofenadine hydrochloride | 苏州卫生职业技术学院 | 2017-06-16 | — | — | CN | claimed |
| CN-104876853-A | Fexofenadine hydrochloride synthesizing method | SUZHOU HEALTH COLLEGE | 2015-09-02 | — | — | CN | claimed |
| EP-2532644-A1 | Preparation of 2-(4-bromophenyl)-2-methylpropanoic acid | Divi's Laboratories Limited (IN) | 2012-12-12 | — | — | EP | claimed |
| US-20120309973-A1 | PREPARATION OF 2-(4-BROMOPHENYL)-2-METHYLPROPANOIC ACID | DIVI'S LABORATORIES LIMITED (IN) | 2012-12-06 | — | — | US | claimed |
| US-12637440-B2 | Amide derivative useful as diacylglycerol acyltransferase 2 inhibitor, and use thereof | LG CHEM, LTD. (KR) | 2026-05-26 | — | — | US | disclosed |
| CN-122094688-A | Compositions and methods for treating pulmonary arterial hypertension | — | 2026-05-26 | — | — | CN | disclosed |
| EP-4702033-A1 | DESMURAMYLPEPTIDE DIACIDS AS NOD2 AGONISTS AND USE THEREOF | Imhotex Limited (GB) | 2026-03-04 | — | — | EP | disclosed |
| US-20250381196-A1 | ALPHA PROTEIN KINASE 1 INHIBITORS FOR USE IN TREATING KIDNEY DISEASES AND KIDNEY-RELATED DISEASES | SHANGHAI YAO YUAN BIOTECHNOLOGY CO LTD (CN) | 2025-12-18 | — | — | US | disclosed |
| US-12459915-B2 | Biaryl derivative useful as diacylglycerol acyltransferase 2 inhibitor, and use thereof | LG CHEM, LTD. (KR) | 2025-11-04 | — | — | US | disclosed |
| US-20250241908-A1 | ALPHA PROTEIN KINASE 1 INHIBITORS FOR USE IN TREATING ATHEROSCLEROSIS AND RELATED DISEASES | NINGBO MEISHAN BONDED PORT AREA ZHEJIANG UNITED INVESTMENT MANAGEMENT CO., LTD. (CN) | 2025-07-31 | — | — | US | disclosed |
| CN-119997953-A | Alpha protein kinase 1 inhibitors for the treatment of kidney diseases and kidney related diseases | 上海药苑生物科技有限公司 | 2025-05-13 | — | — | CN | disclosed |
| EP-4543443-A1 | ALPHA PROTEIN KINASE 1 INHIBITORS FOR USE IN TREATING KIDNEY DISEASES AND KIDNEY-RELATED DISEASES | Shanghai Yao Yuan Biotechnology Co., Ltd. (CN) | 2025-04-30 | — | — | EP | disclosed |
| US-20030220375-A1 | N-biphenyl(substituted methyl) aminocycloalkane-carboxamide derivatives | MERCK SHARP & DOHME LLC | 2003-11-27 | — | — | US | disclosed |
| WO-2003066577-A1 | N-BIPHENYLMETHYL AMINOCYCLOALKANECARBOXAMIDE DERIVATIVES WITH A SUBSTIITUENT ON THE METHYL USEFUL AS BRADYKININ ANTAGONISTS | MERCK & CO., INC. (US) | 2003-08-14 | — | — | WO | disclosed |
| EP-0117302-B1 | PHENOTHIAZINE DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1990-06-27 | — | — | EP | disclosed |
| CN-87103809-A | The method for making of naphthane and indan derivative | — | 1987-12-02 | — | — | CN | disclosed |
| US-4634699-A | ANTIHISTAMINES | BURROUGHS WELLCOME CO. (US) | 1987-01-06 | — | — | US | disclosed |
| EP-0117302-A2 | Phenothiazine derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-09-05 | — | — | EP | disclosed |
| US-4393233-A | FROM ISOBUTYRIC ACID, BROMINE, AND BENZENE | ALLIED CORPORATION (US) | 1983-07-12 | — | — | US | disclosed |
| US-4310655-A | Polymers of p-(1,1-dimethyl-2-hydroxyethyl)benzoic acid and preparation thereof | ALLIED CORPORATION (US) | 1982-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309973-A1 | PREPARATION OF 2-(4-BROMOPHENYL)-2-METHYLPROPANOIC ACID | HRH2, NPFFR2, GABRA6 | KMT2A 141/4885MAPT 1798/4885NPC1 4495/4885 |
| US-20030220375-A1 | N-biphenyl(substituted methyl) aminocycloalkane-carboxamide derivatives | BDKRB1, BDKRB2, CNR2 | KMT2A 771/4885MAPT 4031/4885NPC1 2432/4885 |
| US-20250241908-A1 | ALPHA PROTEIN KINASE 1 INHIBITORS FOR USE IN TREATING ATHEROSCLEROSIS AND RELATED DISEASES | PHKA1, PHKA2, PHKG1 | KMT2A 2582/4885MAPT 1820/4885NPC1 342/4885 |
| US-20250381196-A1 | ALPHA PROTEIN KINASE 1 INHIBITORS FOR USE IN TREATING KIDNEY DISEASES AND KIDNEY-RELATED DISEASES | PHKA1, PHKA2, PHKG1 | KMT2A 2191/4885MAPT 1740/4885NPC1 1064/4885 |
| US-12637440-B2 | Amide derivative useful as diacylglycerol acyltransferase 2 inhibitor, and use thereof | DGAT2, DGAT1, DLAT | KMT2A 738/4885MAPT 4369/4885NPC1 278/4885 |
| US-12459915-B2 | Biaryl derivative useful as diacylglycerol acyltransferase 2 inhibitor, and use thereof | DGAT2, DGAT1, LCAT | KMT2A 681/4885MAPT 2249/4885NPC1 286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.