Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 10/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9679943 | 0.90 | GSK3B (0.51) | GSK3BALDH1A1SMN1; SMN2MAPK1TSHR | |
| SCHEMBL9315390 | 0.86 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MAPK1TSHRMAPT | |
| SCHEMBL27615283 | 0.86 | GSK3B (0.50) | GSK3BALDH1A1SMN1; SMN2MAPK1TSHR | |
| SCHEMBL10383859 | 0.84 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2MAPK1TSHRMAPT | |
| SCHEMBL8898770 | 0.83 | GSK3B (0.47) | GSK3BALDH1A1SMN1; SMN2MAPK1TSHR | |
| SCHEMBL9680425 | 0.83 | ALDH1A1 (0.68) | GSK3BALDH1A1SMN1; SMN2MAPK1TSHR | |
| SCHEMBL9679470 | 0.81 | GSK3B (0.52) | GSK3BALDH1A1SMN1; SMN2MAPK1TSHR | |
| SCHEMBL27634291 | 0.80 | GSK3B (0.49) | GSK3BALDH1A1SMN1; SMN2MAPK1MAPT | |
| SCHEMBL9679918 | 0.80 | ALDH1A1 (0.64) | GSK3BALDH1A1SMN1; SMN2MAPK1TSHR | |
| SCHEMBL9681606 | 0.80 | GSK3B (0.46) | GSK3BALDH1A1SMN1; SMN2MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| US-4960746-A | A-HYDROXY-OR A-AMINO-ACETOPHENONES AND A TITANOCENE COMPOUND SUBSTITUTED BY FLUORINE | CIBA-GEIGY CORPORATION (US) | 1990-10-02 | — | — | US | disclosed |