Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 9/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9679470 | 0.90 | GSK3B (0.52) | GSK3BMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL10384862 | 0.88 | ALDH1A1 (0.42) | MAPTSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL27615283 | 0.87 | GSK3B (0.50) | GSK3BMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9679954 | 0.86 | ALDH1A1 (0.41) | MAPTSMN1; SMN2LMNAALDH1A1MEN1 | |
| SCHEMBL10384867 | 0.86 | ALDH1A1 (0.62) | MAPTSMN1; SMN2NPC1LMNAL3MBTL1 | |
| SCHEMBL9681257 | 0.86 | ALDH1A1 (0.44) | MAPTSMN1; SMN2LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL8900852 | 0.82 | GSK3B (0.45) | GSK3BMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8898382 | 0.82 | GSK3B (0.45) | GSK3BMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8900208 | 0.81 | GSK3B (0.44) | GSK3BMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL28936310 | 0.81 | SMN1; SMN2 (0.49) | GSK3BMAPTSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| US-4960746-A | A-HYDROXY-OR A-AMINO-ACETOPHENONES AND A TITANOCENE COMPOUND SUBSTITUTED BY FLUORINE | CIBA-GEIGY CORPORATION (US) | 1990-10-02 | — | — | US | disclosed |