Known targets — ChEMBL curated mechanism
ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2BTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3MPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PPARGSLC6A2SLC6A3SLC6A4SMOTYK2pol
The experimentally established mechanism targets of Maleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 4/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HCAR2 | Q8TDS4 | 8/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL956152 | 1.00 | TSHR (0.79) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Fumaric Acid SCHEMBL30592706 | 1.00 | TSHR (0.79) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL29132468 | 0.96 | TSHR (0.73) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Acrylic Acid SCHEMBL27491143 | 0.91 | TSHR (0.86) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Acrylic Acid SCHEMBL1665306 | 0.91 | TSHR (0.86) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Acrylic Acid SCHEMBL28805889 | 0.91 | TSHR (0.86) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Hydrogen Peroxide SCHEMBL9125524 | 0.91 | TSHR (0.95) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL29185571 | 0.89 | TSHR (0.63) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Monomethyl Fumarate SCHEMBL28099233 | 0.89 | TSHR (0.63) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Maleic Acid SCHEMBL3892059 | 0.89 | TSHR (0.67) | TSHRALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215194-A1 | ENHANCED REMOVABILITY OF NAIL COATINGS USING ACIDIC COPOLYMERS FOR TRIGGERED REMOVAL WITH AQUEOUS BASED REMOVER | ARKEMA FRANCE (FR) | 2025-10-16 | — | — | WO | claimed |
| WO-2025215193-A1 | ACIDIC OLIGOMERS USED IN DEINKING PROCESS | ARKEMA FRANCE (FR) | 2025-10-16 | — | — | WO | disclosed |
| WO-2025215194-A1 | ENHANCED REMOVABILITY OF NAIL COATINGS USING ACIDIC COPOLYMERS FOR TRIGGERED REMOVAL WITH AQUEOUS BASED REMOVER | ARKEMA FRANCE (FR) | 2025-10-16 | — | — | WO | disclosed |
| CN-110546134-B | Oxime ester compound and photopolymerization initiator containing the same | 株式会社艾迪科 | 2024-12-20 | — | — | CN | disclosed |
| CN-116888232-A | Adhesive for display device and adhesive sheet using same | 株式会社巴川制纸所 | 2023-10-13 | — | — | CN | disclosed |
| CN-116640261-A | Silicon-containing vegetable oil-based dual UV (ultraviolet) curing material and preparation method and application thereof | 华南农业大学 | 2023-08-25 | — | — | CN | disclosed |
| CN-108475019-B | Black photosensitive resin composition | 株式会社艾迪科 | 2022-02-11 | — | — | CN | disclosed |
| CN-112004800-A | Oxime ester compound and photopolymerization initiator containing the same | 株式会社ADEKA | 2020-11-27 | — | — | CN | disclosed |
| CN-111132963-A | Compound, composition, cured product, and method for producing cured product | 株式会社艾迪科 | 2020-05-08 | — | — | CN | disclosed |
| CN-106470971-B | Novel polymerization initiator and radical polymerizable composition containing the same | 株式会社艾迪科 | 2020-03-03 | — | — | CN | disclosed |
| US-20080070998-A1 | Foam Production Method | OJI PAPER CO., LTD. (JP) | 2008-03-20 | — | — | US | disclosed |
| EP-1795553-A1 | PROCESS FOR PRODUCING FOAM | Oji Paper Co., Ltd. (JP) | 2007-06-13 | — | — | EP | disclosed |
| US-20060210785-A1 | Foamed product in a sheet form and method for production thereof | OJI PAPER CO., LTD. (JP) | 2006-09-21 | — | — | US | disclosed |
| EP-1647570-A1 | FOAMED PRODUCT IN A SHEET FORM AND METHOD FOR PRODUCTION THEREOF | Oji Paper Co., Ltd. (JP) | 2006-04-19 | — | — | EP | disclosed |
| CN-1682149-A | Liquid crystal sealing composition and method for manufacturing liquid crystal display panel using the same | MITSUI CHEMICALS INC (JP) | 2005-10-12 | — | — | CN | disclosed |
| EP-0872529-B1 | BINDER FOR BUILDING STRUCTURES | ASAHI CHEMICAL IND (JP) | 2004-09-29 | — | — | EP | disclosed |
| US-6015845-A | Binder for building structure | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 2000-01-18 | — | — | US | disclosed |
| EP-0872529-A1 | BINDER FOR BUILDING STRUCTURES | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1998-10-21 | — | — | EP | disclosed |
| US-4914172-A | BIODEGRADABLE SEED COATINGS | BASF AKTIENGESELLSCHAFT (DE) | 1990-04-03 | — | — | US | disclosed |
| US-3940349-A | Compositions and process for making rigid plastic foams of modified vinyl ester resins and silicone compounds | THE DOW CHEMICAL COMPANY (US) | 1976-02-24 | — | — | US | disclosed |