SCHEMBL9681126

SCHEMBL9681126

O=S(=O)(O)c1ccccc1-c1ccc2ccccc2c1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTRB1 P17538 1/20 0.52
MPL P40238 3/20 0.47
CTRC Q99895 2/20 0.47
PTPN22 Q9Y2R2 1/20 0.44
KDM4A O75164 1/20 0.44
USP2 O75604 1/20 0.44
NSD2 O96028 1/20 0.44
ALPL P05186 1/20 0.44
PLCG1 P19174 1/20 0.44
TNNI3 P19429 1/20 0.44
NFKB1 P19838 1/20 0.44
TNNT2 P45379 1/20 0.44
MMP14 P50281 1/20 0.44
CASP6 P55212 1/20 0.44
TNNC1 P63316 1/20 0.44
KDM4C Q9H3R0 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
DNMT1 P26358 1/20 0.42
LDHA P00338 1/20 0.42
CYP2D6 P10635 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4360130 0.82 CA1 (0.50) CTRB1MPLCTRCHCRTR1CA1
SCHEMBL28210690 0.81 CTRB1 (0.47) CTRB1MPLCTRCCYP2D6HCRTR1
SCHEMBL30383446 0.80 CTRB1 (0.64) CTRB1MPLCTRCPTPN22LDHA
Hydrochloric Acid SCHEMBL27766336 0.80 CTRB1 (0.64) CTRB1MPLCTRCPTPN22LDHA
SCHEMBL88069 0.80 CTRB1 (0.64) CTRB1MPLCTRCPTPN22LDHA
SCHEMBL29401627 0.80 PTPN22 (0.65) PTPN22USP2LDHACYP2D6CYP1A2
SCHEMBL374807 0.80 PTPN22 (0.65) PTPN22USP2LDHACYP2D6CYP1A2
Potassium SCHEMBL2292044 0.79 CTRB1 (0.62) CTRB1MPLCTRCPTPN22LDHA
SCHEMBL7158072 0.79 CTRB1 (0.62) CTRB1MPLCTRCPTPN22LDHA
Ammonia Solution, Strong SCHEMBL7758965 0.79 CTRB1 (0.62) CTRB1MPLCTRCPTPN22LDHA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5128455-A WATER-SOLUBLE FIBER-REACTIVE DYES, CONTAINING AN AMINO-SUBSTITUTED 5-TRIAZINE RING WITH A FIBER-REACTIVE GROUP OF THE VINYLSULFONE SERIES HOECHST AKTIENGESELLSCHAFT (DE) 1992-07-07 US disclosed