SCHEMBL4360130

SCHEMBL4360130

O=S(=O)(O)c1ccccc1-c1cccc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA9 Q16790 2/20 0.50
CASP1 P29466 1/20 0.48
TTR P02766 2/20 0.47
CHAT P28329 1/20 0.46
SNCA P37840 1/20 0.46
F2 P00734 2/20 0.46
PRSS1 P07477 2/20 0.46
PRSS2 P07478 2/20 0.46
PRSS3 P35030 2/20 0.46
CA12 O43570 1/20 0.45
PTPN1 P18031 1/20 0.43
CTRB1 P17538 1/20 0.43
GPR84 Q9NQS5 1/20 0.43
FABP4 P15090 1/20 0.42
CCNA2 P20248 1/20 0.42
CDK2 P24941 1/20 0.42
MAPK14 Q16539 1/20 0.42
HTR6 P50406 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15851425 0.92 TTR (0.56) CA1CA2CA9CASP1TTR
SCHEMBL28210690 0.87 CTRB1 (0.47) CA1CA2CA9CASP1TTR
Sulfuric Acid SCHEMBL28288453 0.86 CA1 (0.52) CA1CA2CA9F2PRSS1
SCHEMBL11161300 0.84 CA1 (0.53) CA1CA2CA9CASP1F2
SCHEMBL30304762 0.84 CA1 (0.63) CA1CA2CA9TTRF2
SCHEMBL29358913 0.84 CA1 (0.63) CA1CA2CA9TTRF2
SCHEMBL4323 0.84 CA1 (0.63) CA1CA2CA9TTRF2
SCHEMBL27719293 0.84 CA1 (0.63) CA1CA2CA9TTRF2
SCHEMBL458284 0.83 SMN1; SMN2 (0.48) CA1CA2CA9TTRCHAT
SCHEMBL3909203 0.82 CA1 (0.52) CA1CA2CA9CASP1F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112130416-A Photoetching material, display substrate, manufacturing method of display substrate and display panel 北京京东方技术开发有限公司 2020-12-25 CN claimed
CN-112130416-A Photoetching material, display substrate, manufacturing method of display substrate and display panel 北京京东方技术开发有限公司 2020-12-25 CN disclosed
CN-101516353-B controlled release oral formulations comprising a core and one or more barrier layers JAGOTEC AG 2013-10-16 CN disclosed
US-8273685-B2 Agrochemical composition NIPPON SODA CO., LTD. (JP) 2012-09-25 US disclosed
CN-102686629-A Polymers for contact lenses OCUTEC LTD 2012-09-19 CN disclosed
CN-102686630-A Polymers for contact lenses OCUTEC LTD 2012-09-19 CN disclosed
US-20090286682-A1 AGROCHEMICAL COMPOSITION NIPPON SODA CO., LTD. (JP) 2009-11-19 US disclosed
CN-101516353-A Controlled release oral formulations comprising a core and one or more barrier layers JAGOTEC AG (CH) 2009-08-26 CN disclosed
CN-101516352-A Controlled release solid oral formulations comprising nisoldipine JAGOTEC AG (CH) 2009-08-26 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090286682-A1 AGROCHEMICAL COMPOSITION DEGS1, PFAS, SGMS1 CA1 1993/4885CA2 1485/4885CA9 3288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.