Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TACR3 | P29371 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28845914 | 0.74 | SMN1; SMN2 (0.49) | SMN1; SMN2OPRM1OPRD1GAALMNA | |
| SCHEMBL3312757 | 0.73 | SMN1; SMN2 (0.58) | SMN1; SMN2OPRM1OPRD1GAALMNA | |
| SCHEMBL19070596 | 0.73 | SMN1; SMN2 (0.77) | SMN1; SMN2OPRM1OPRD1LMNATSHR | |
| SCHEMBL4541997 | 0.73 | KCNA5 (0.48) | SMN1; SMN2OPRM1OPRD1GAALMNA | |
| SCHEMBL18889556 | 0.72 | OPRM1 (0.60) | SMN1; SMN2OPRM1OPRD1GAALMNA | |
| SCHEMBL29005260 | 0.71 | SMN1; SMN2 (0.68) | SMN1; SMN2OPRM1OPRD1LMNAKMT2A | |
| SCHEMBL18765527 | 0.71 | OPRM1 (0.49) | SMN1; SMN2OPRM1OPRD1LMNAKMT2A | |
| SCHEMBL96865 | 0.71 | ALDH1A1 (0.56) | SMN1; SMN2KMT2APOLBMEN1ALDH1A1 | |
| SCHEMBL11541847 | 0.71 | SMN1; SMN2 (0.54) | SMN1; SMN2OPRM1OPRD1GAALMNA | |
| SCHEMBL11541844 | 0.71 | SMN1; SMN2 (0.54) | SMN1; SMN2OPRM1OPRD1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |