Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 3/20 | 0.52 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735708 | 0.85 | THRA (0.52) | THRATHRBFFAR4S1PR1FFAR1 | |
| SCHEMBL7733967 | 0.84 | FFAR4 (0.50) | THRATHRBFFAR4S1PR1FFAR1 | |
| SCHEMBL9362335 | 0.83 | THRA (0.54) | THRATHRBRXRAFFAR4S1PR1 | |
| SCHEMBL7420826 | 0.80 | PDE4A (0.57) | THRATHRBHDAC1HDAC2PDE4A | |
| SCHEMBL3883711 | 0.80 | FFAR4 (0.57) | THRATHRBFFAR4S1PR1FFAR1 | |
| SCHEMBL3881792 | 0.80 | FFAR4 (0.45) | THRATHRBFFAR4S1PR1PDE4B | |
| SCHEMBL7735139 | 0.79 | FFAR4 (0.48) | THRATHRBFFAR4HDAC1HDAC2 | |
| SCHEMBL7335293 | 0.79 | PDE4A (0.58) | THRATHRBHDAC1HDAC2PDE4A | |
| SCHEMBL31254180 | 0.79 | THRA (0.52) | THRATHRBFFAR4S1PR1FFAR1 | |
| SCHEMBL3679192 | 0.78 | FFAR4 (0.58) | THRATHRBFFAR4S1PR1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470832-A2 | Biphenyl 5,5'-bis-alkanoic acid derivatives, their production and use thereof | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1992-02-12 | — | — | EP | disclosed |