Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10886422 | 0.89 | ALDH1A1 (0.53) | MAPTTSHRALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL2319695 | 0.84 | ALDH1A1 (0.59) | MAPTTSHRALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL10891993 | 0.79 | ALDH1A1 (0.61) | MAPTTSHRALDH1A1MAPK1SMN1; SMN2 | |
| Trimetozine SCHEMBL114786 | 0.78 | MAPT (0.72) | MAPTALDH1A1POLBKMT2ACYP1A2 | |
| SCHEMBL9681207 | 0.78 | ALDH1A1 (0.52) | MAPTTSHRALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL3669987 | 0.77 | ALDH1A1 (0.47) | MAPTTSHRALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL9681204 | 0.77 | ALDH1A1 (0.51) | MAPTTSHRALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL10889434 | 0.77 | ALDH1A1 (0.61) | MAPTTSHRALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL275396 | 0.77 | ALDH1A1 (0.65) | MAPTTSHRALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL28896786 | 0.75 | L3MBTL1 (0.65) | TSHRALDH1A1MAPK1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |