Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 5/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681988 | 0.84 | TDP1 (0.54) | PARP15PARP10PARP2CHEK1TDP1 | |
| SCHEMBL321216 | 0.84 | TDP1 (0.54) | PARP15PARP10PARP2CHEK1TDP1 | |
| SCHEMBL1928007 | 0.80 | TSHR (0.46) | PARP15PARP10PARP2CHEK1TDP1 | |
| SCHEMBL11254102 | 0.78 | TDP1 (0.51) | PARP15PARP10PARP2TDP1 | |
| SCHEMBL321289 | 0.78 | ADRB1 (0.50) | PARP15PARP10PARP2CHEK1SIGMAR1 | |
| SCHEMBL9681242 | 0.78 | TDP1 (0.44) | PARP15PARP10PARP2CHEK1TDP1 | |
| SCHEMBL8989368 | 0.77 | PARP15 (0.50) | PARP15PARP10PARP2CHEK1TDP1 | |
| SCHEMBL29024848 | 0.76 | PARP15 (0.64) | PARP15PARP10PARP2TDP1SIGMAR1 | |
| SCHEMBL11248061 | 0.75 | LTA4H (0.51) | — | |
| SCHEMBL10633504 | 0.75 | CHEK1 (0.39) | PARP15PARP10PARP2CHEK1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0498705-A1 | Phenol ethers derivatives, their preparation and their therapeutical use | SYNTHELABO (FR) | 1992-08-12 | — | — | EP | disclosed |